Molecular Fluorescence Guided Surgery

In Fluorescence Guided Surgery, the goal is to achieve a better real-time detection of malignant lesions and lymph node metastases using near-infrared (NIR) optical tracers during surgery.


The main focus of the Optical Molecular Imaging Groningen research group and the research-line Molecular Fluorescence Image Guided Surgery and Pathology, is translational bio-optical imaging and therapy in cancer and infectious diseases, i.e. image-guided surgery and pathology, laparoscopy, and  the near future also robotics, for the detection of tumor cells and locoregional metastases including so-called photo-immunotherapy and bacterial detection in lung or implant infections.


Bio-optical imaging may provide the surgeon with light-beacons for radical excision of tumor tissue or lymph node dissections and in case of irradical resection a tool for guidance for intraoperative radiotherapy or targeted therapeutic modalities like targeted radiotherapy and photodynamic therapy. Translational research in bio-optical imaging relates to various fields of medicine and in particular surgery, pathology, medical imaging and endoscopy in solid tumors.